Across TCGA pan-cancer cohorts, SNHG5 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SNHG5 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher SNHG5 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SNHG5 expression acts as an unfavorable survival marker.

HNSC, LUAD, and UCEC are the cancer types where SNHG5 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	II,III,IV	0.118	0.756	<.001	42	view →
LUAD	OS	Median	All	0.238	0.697	.015	9	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: SNHG5 tumor-vs-normal RNA expression · all SNHG5 data types