SNHG4

Across TCGA pan-cancer cohorts, SNHG4 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated SNHG4 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher SNHG4 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SNHG4 expression acts as an unfavorable survival marker, although some lineages such as READ and LUSC show a favorable association.

KIRC, KICH, and KIRP are the cancer types where SNHG4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.756	0.848	<.001	123	view →
KICH	DFS	Median	II,III,IV	0.660	1.000	<.001	93	view →
KIRP	DFS	Median	All	0.359	0.706	<.001	91	view →
UVM	DFS	Median	III,IV	0.319	0.797	<.001	70	view →
READ	OS	Median	II,III,IV	0.881	0.389	<.001	70	view →
LIHC	DFS	Quartile	All	0.362	0.590	<.001	66	view →
LGG	DFS	Median	All	0.634	0.844	<.001	54	view →
UCEC	DFS	Quartile	All	0.584	0.718	.002	42	view →
SARC	OS	Median	All	0.420	0.597	<.001	34	view →
BLCA	DFS	Tertile	All	0.446	0.695	.006	22	view →
ACC	DFS	Tertile	IV	0.096	0.610	<.001	21	view →
CESC	OS	Median	All	0.825	0.924	.002	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

SNHG4–KIRC (DFS)

Open the KIRC breakdown →