SNHG28

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, SNHG28 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated SNHG28 data layer compared with 1 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher SNHG28 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SNHG28 expression acts as an unfavorable survival marker, although some lineages such as KIRP and READ show a favorable association.

KIRC, KIRP, and READ are the cancer types where SNHG28 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCDFSTertileAll0.5480.719<.00190view →
KIRPDFSTertileAll1.0000.565.00155view →
READOSTertileII,III,IV0.8090.270.00152view →
PAADDFSMedianAll0.5580.407.00344view →
MESOOSQuartileIV0.1780.794.02020view →
SKCMDFSQuartileII,III,IV0.3660.212.00819view →
ACCDFSTertileAll0.5430.851.00115view →
STADDFSMedianIV0.1380.604.02412view →
UCSDFSMedianIII,IV0.5650.276.01612view →
BRCADFSTertileII,III,IV0.9270.961.01711view →
LUSCOSTertileIII,IV0.5420.768.02510view →
HNSCOSMedianIV0.5430.332.0239view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

Exploration