SNHG27

Across TCGA pan-cancer cohorts, SNHG27 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated SNHG27 data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher SNHG27 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SNHG27 expression acts as an unfavorable survival marker, although some lineages such as ESCA and PAAD show a favorable association.

CESC, KICH, and ESCA are the cancer types where SNHG27 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Tertile	II,III,IV	0.186	0.573	.002	102	view →
KICH	DFS	Tertile	II,III,IV	0.043	0.950	<.001	66	view →
ESCA	OS	Median	II,III,IV	0.640	0.372	.001	62	view →
BLCA	OS	Quartile	III,IV	0.537	0.728	.001	52	view →
KIRC	DFS	Quartile	IV	0.317	0.549	.004	45	view →
THCA	DFS	Tertile	II,III,IV	0.801	0.954	<.001	42	view →
STAD	DFS	Quartile	All	0.177	0.440	.003	38	view →
DLBC	OS	Tertile	II,III,IV	0.118	0.802	.025	36	view →
UCEC	DFS	Tertile	All	0.826	0.906	.019	18	view →
LIHC	OS	Tertile	All	0.417	0.556	.011	17	view →
LGG	DFS	Tertile	All	0.588	0.750	.017	12	view →
PAAD	DFS	Tertile	II,III,IV	0.616	0.411	.045	5	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

SNHG27–CESC (DFS)

Open the CESC breakdown →