SNHG15

Across TCGA pan-cancer cohorts, SNHG15 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated SNHG15 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher SNHG15 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SNHG15 expression acts as an unfavorable survival marker, although some lineages such as CHOL and THCA show a favorable association.

KIRC, ACC, and LIHC are the cancer types where SNHG15 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.517	0.729	<.001	144	view →
ACC	DFS	Median	All	0.189	0.731	<.001	117	view →
LIHC	OS	Median	All	0.705	0.854	<.001	67	view →
KICH	DFS	Median	III,IV	0.308	0.942	.001	60	view →
UVM	DFS	Quartile	All	0.495	0.872	.004	45	view →
CHOL	DFS	Tertile	II,III,IV	0.534	0.123	.001	42	view →
PRAD	DFS	Median	All	0.674	0.901	<.001	26	view →
SARC	OS	Tertile	All	0.590	0.867	<.001	22	view →
KIRP	DFS	Tertile	III,IV	0.110	0.579	<.001	21	view →
UCEC	DFS	Tertile	All	0.846	0.930	.003	20	view →
COAD	OS	Quartile	All	0.780	0.925	.005	16	view →
OV	DFS	Median	IV	0.356	0.548	.008	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

SNHG15–KIRC (DFS)

Open the KIRC breakdown →