SNF8

Across TCGA pan-cancer cohorts, SNF8 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated SNF8 data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher SNF8 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SNF8 expression acts as an unfavorable survival marker, although some lineages such as UCEC and CCRCC show a favorable association.

UCEC, CCRCC, and PDAC are the cancer types where SNF8 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	II,III,IV	0.944	0.481	.003	26	view →
CCRCC	DFS	Tertile	II,III,IV	0.928	0.105	.006	20	view →
PDAC	DFS	Median	II,III,IV	0.468	0.253	.004	19	view →
COAD	DFS	Median	All	1.000	0.888	.022	18	view →
LUAD	DFS	Quartile	All	0.919	0.491	.016	9	view →
HNSC	DFS	Median	II,III,IV	0.901	0.987	.026	5	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

SNF8–UCEC (DFS)

Open the UCEC breakdown →