SNF8

Across TCGA patient cohorts, SNF8 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNF8-associated genes across cancer lineages are Rad50 and Annexin-1. Each is linked with SNF8 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNF8-to-partner and partner-to-SNF8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rad50 grouped by SNF8-low versus SNF8-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNF8→partner) and Y-score (partner→SNF8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Rad50 →	-0.329	-3.000	.018	.037	2	1
UCEC	Annexin-1 →	+0.952	+3.000	.001	.037	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Rad50 by SNF8 expression — UCEC

Explore this box plot interactively →