SNF8

Across TCGA cell cohorts, SNF8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,476 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible SNF8-associated GO terms across cancer lineages are Transcription initiation at RNA polymerase II promoter, Protein-DNA complex assembly, and Positive regulation of mitotic cytokinesis. Each is linked with SNF8 in more than 10 cancer types. Because this analysis shows association rather than direction, both SNF8-to-partner and partner-to-SNF8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription initiation at RNA polymerase II promoter grouped by SNF8-low versus SNF8-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SNF8→partner) and Y-score (partner→SNF8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Transcription initiation at RNA polymerase II promoter →	+0.081	+0.900	<.001	.002	3	11
LUNG_NSCLC_LUSC	Protein-DNA complex assembly →	+0.065	+0.851	<.001	.004	3	11
BLOOD_Myeloma	Positive regulation of mitotic cytokinesis →	+0.178	+1.474	<.001	<.001	3	11
PANCREAS	Spindle elongation →	+0.311	+0.974	<.001	<.001	3	11
BLOOD_Myeloma	Spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) →	+0.092	+1.218	.006	.003	3	11
LUNG_NSCLC_LUSC	Anatomical structure homeostasis →	-0.082	-0.855	.008	.003	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,476 associations by consensus.

Transcription initiation at RNA polymerase II promoter by SNF8 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →