SNED1

Across TCGA pan-cancer cohorts, SNED1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SNED1 data layer compared with 23 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher SNED1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated SNED1 expression acts as an unfavorable survival marker.

UCEC, PDAC, and LUAD are the cancer types where SNED1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	III,IV	0.494	1.000	.016	30	view →
PDAC	OS	Median	All	0.257	0.565	<.001	30	view →
LUAD	DFS	Tertile	III,IV	0.471	0.968	.031	6	view →
LSCC	OS	Median	II,III,IV	0.901	1.000	.016	5	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SNED1–UCEC (OS)

Open the UCEC breakdown →