Across TCGA patient cohorts, SND1 mutation is significantly associated with the total protein of many other genes, with 58 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SND1-associated genes across cancer lineages are ATM, Caveolin-1, and HER3_pY1289. Each is linked with SND1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SND1-to-partner and partner-to-SND1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SND1→partner) and Y-score (partner→SND1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.535	-1.830	<.001	<.001	3	3
SKCM	Caveolin-1 →	-0.783	-3.169	.006	.018	3	3
LUAD	HER3_pY1289 →	+0.126	+2.820	.012	.035	3	2
LUAD	TSC1 →	-0.561	-3.000	.001	.034	3	2
LUAD	4E-BP1_pT70 →	+0.271	+2.186	.004	.034	3	2
UCEC	4E-BP1 →	+0.336	+1.830	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 58 associations by consensus.

Exploration

SND1 survival (RNA) · tumor vs normal (RNA) · all SND1 data types