SNAPC5

Across TCGA pan-cancer cohorts, SNAPC5 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated SNAPC5 data layer compared with 26 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher SNAPC5 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SNAPC5 expression acts as an unfavorable survival marker, although some lineages such as HNSC and CCRCC show a favorable association.

HNSC, CCRCC, and LUAD are the cancer types where SNAPC5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.855	0.349	.024	8	view →
CCRCC	DFS	Quartile	III,IV	0.757	0.172	.006	7	view →
LUAD	DFS	Median	All	0.899	1.000	.004	4	view →
PDAC	OS	Median	III,IV	1.000	0.651	.008	3	view →
LSCC	OS	Median	All	0.773	1.000	.042	2	view →
GBM	OS	Quartile	All	0.693	1.000	.024	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

SNAPC5–HNSC (DFS)

Open the HNSC breakdown →