SNAPC5

Across TCGA patient cohorts, SNAPC5 mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNAPC5-associated genes across cancer lineages are RN7SL43P, RNU6-492P, and RNU4-26P. Each is linked with SNAPC5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNAPC5-to-partner and partner-to-SNAPC5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL43P grouped by SNAPC5-low versus SNAPC5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNAPC5→partner) and Y-score (partner→SNAPC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL43P →	+0.206	+2.812	.002	.008	3	1
HNSC	RNU6-492P →	+0.478	+7.954	<.001	.008	3	1
HNSC	RNU4-26P →	+0.268	+7.954	<.001	.008	3	1
UCEC	MIR548AI →	+0.317	+4.928	<.001	.002	3	1
UCEC	FTLP5 →	+0.236	+2.861	.009	.009	3	1
UCEC	IL21 →	+0.241	+3.026	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

RN7SL43P by SNAPC5 expression — UCEC

Explore this box plot interactively →