SNAPC5

Across TCGA cell cohorts, SNAPC5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,094 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible SNAPC5-associated GO terms across cancer lineages are Regulation of DNA replication, RNA splicing, via transesterification reactions, and Nucleobase biosynthetic process. Each is linked with SNAPC5 in more than 10 cancer types. Because this analysis shows association rather than direction, both SNAPC5-to-partner and partner-to-SNAPC5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA replication grouped by SNAPC5-low versus SNAPC5-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SNAPC5→partner) and Y-score (partner→SNAPC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of DNA replication →	+0.072	+0.845	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	RNA splicing, via transesterification reactions →	+0.070	+0.755	.009	.002	3	10
UPPER_AERODIGESTIVE_TRACT	Nucleobase biosynthetic process →	+0.158	+0.817	.001	.003	3	10
UPPER_AERODIGESTIVE_TRACT	Mitotic cell cycle checkpoint signaling →	+0.094	+0.782	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) →	+0.093	+0.920	.006	<.001	3	10
LIVER	Mitotic intra-S DNA damage checkpoint signaling →	+0.115	+0.737	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,094 associations by consensus.

Regulation of DNA replication by SNAPC5 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →