SNAPC4

Across TCGA pan-cancer cohorts, SNAPC4 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated SNAPC4 data layer compared with 4 for mutation status and 7 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher SNAPC4 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SNAPC4 expression acts as an unfavorable survival marker, although some lineages such as UVM and SCLC show a favorable association.

ACC, MESO, and KIRC are the cancer types where SNAPC4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.193	0.688	<.001	135	view →
MESO	OS	Tertile	II,III,IV	0.422	0.723	<.001	73	view →
KIRC	DFS	Median	IV	0.467	0.757	<.001	65	view →
UVM	OS	Tertile	All	0.932	0.479	.002	60	view →
BLCA	DFS	Quartile	All	0.371	0.782	<.001	41	view →
LIHC	DFS	Median	All	0.475	0.605	.001	39	view →
COAD	OS	Median	All	0.826	0.907	.003	36	view →
SCLC	DFS	Median	II,III,IV	0.819	0.205	.004	31	view →
PAAD	OS	Tertile	All	0.548	0.255	.002	23	view →
READ	OS	Median	All	0.771	0.529	.005	17	view →
CESC	DFS	Median	All	0.774	0.865	.018	16	view →
CHOL	OS	Median	II,III,IV	0.862	0.317	.017	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

SNAPC4–ACC (DFS)

Open the ACC breakdown →