SNAPC3

Across TCGA pan-cancer cohorts, SNAPC3 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SNAPC3 data layer compared with 21 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher SNAPC3 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated SNAPC3 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

CCRCC, LUAD, and UCEC are the cancer types where SNAPC3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	All	0.791	0.963	.011	2	view →
LUAD	OS	Median	All	0.799	1.000	.020	2	view →
UCEC	DFS	Tertile	All	0.754	0.922	.038	2	view →
HNSC	DFS	Tertile	III,IV	0.660	0.374	.047	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SNAPC3–CCRCC (OS)

Open the CCRCC breakdown →