SNAPC3

Across TCGA patient cohorts, SNAPC3 mutation is significantly associated with the RNA expression of many other genes, with 645 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNAPC3-associated genes across cancer lineages are TRAJ30, LINC00502, and TRAJ10. Each is linked with SNAPC3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNAPC3-to-partner and partner-to-SNAPC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRAJ30 grouped by SNAPC3-low versus SNAPC3-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNAPC3→partner) and Y-score (partner→SNAPC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TRAJ30 →	+1.241	+4.081	<.001	.004	3	2
LUAD	LINC00502 →	+0.114	+5.888	<.001	.002	3	2
UCEC	TRAJ10 →	+0.655	+2.161	<.001	.005	3	2
BRCA	MTND1P35 →	+0.074	+7.731	<.001	.009	3	1
BRCA	SNORD115-39 →	+0.380	+7.731	<.001	.009	3	1
COAD	RNA5SP457 →	+0.465	+3.792	.007	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 645 associations by consensus.

TRAJ30 by SNAPC3 expression — COAD

Explore this box plot interactively →