SNAPC2

Across TCGA patient cohorts, SNAPC2 mutation is significantly associated with the RNA expression of many other genes, with 68 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SNAPC2-associated genes across cancer lineages are RNU6-264P, FARSBP1, and SCGB1D4. Each is linked with SNAPC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNAPC2-to-partner and partner-to-SNAPC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-264P grouped by SNAPC2-low versus SNAPC2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNAPC2→partner) and Y-score (partner→SNAPC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-264P →	+0.174	+3.625	<.001	.004	3	2
UCEC	FARSBP1 →	+0.076	+2.967	.008	.007	3	2
BLCA	SCGB1D4 →	+0.079	+4.497	.001	.009	3	1
BLCA	RNU6-552P →	+0.396	+5.691	<.001	<.001	3	1
BLCA	MIR633 →	+0.311	+5.018	<.001	.004	3	1
SKCM	H2AC1 →	+0.065	+4.343	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 68 associations by consensus.

RNU6-264P by SNAPC2 expression — SKCM

Explore this box plot interactively →