SNAPC1

Across TCGA patient cohorts, SNAPC1 mutation is significantly associated with the RNA expression of many other genes, with 925 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNAPC1-associated genes across cancer lineages are OSBPL9P5, FXYD6P1, and OR9G1. Each is linked with SNAPC1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SNAPC1-to-partner and partner-to-SNAPC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OSBPL9P5 grouped by SNAPC1-low versus SNAPC1-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNAPC1→partner) and Y-score (partner→SNAPC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	OSBPL9P5 →	+0.267	+6.442	<.001	.001	3	3
COAD	FXYD6P1 →	+0.396	+4.126	<.001	.004	3	2
BLCA	OR9G1 →	+0.105	+5.106	<.001	.008	3	1
BLCA	MAGEB5 →	+0.055	+5.788	.004	.003	3	1
BLCA	RNU1-65P →	+0.964	+6.289	<.001	.001	3	1
BLCA	RNA5SP72 →	+0.510	+5.177	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 925 associations by consensus.

OSBPL9P5 by SNAPC1 expression — BRCA

Explore this box plot interactively →