SNAP91

Across TCGA pan-cancer cohorts, SNAP91 Mutation is linked to patient survival in 7 of 34 cancer types, making it a survival-associated SNAP91 data layer compared with 21 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher SNAP91 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SNAP91 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

STAD, ESCA, and PRAD are the cancer types where SNAP91 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Median	II,III,IV	0.184	0.710	.001	18	view →
ESCA	OS	Median	All	0.280	0.715	<.001	18	view →
PRAD	OS	Median	All	0.145	0.883	<.001	12	view →
GBM	DFS	Median	All	0.071	0.288	.009	6	view →
UCEC	DFS	Median	II,III,IV	0.915	0.436	.026	6	view →
COAD	OS	Median	III,IV	0.163	0.791	.004	6	view →
SKCM	DFS	Median	III,IV	0.155	0.653	.017	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

SNAP91–STAD (OS)

Open the STAD breakdown →