SNAP91

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SNAP91 mutation is significantly associated with the RNA expression of many other genes, with 5,442 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNAP91-associated genes across cancer lineages are RNA5SP420, AMD1, and RN7SKP181. Each is linked with SNAP91 in more than 3 cancer types. Because this analysis shows association rather than direction, both SNAP91-to-partner and partner-to-SNAP91 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP420 grouped by SNAP91-low versus SNAP91-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNAP91→partner) and Y-score (partner→SNAP91) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADRNA5SP420 →+0.214+4.485.001.00734
UCECAMD1 →+0.431+2.736.001<.00134
CESCRN7SKP181 →+0.152+5.144<.001.00333
CESCRN7SL134P →+0.196+4.874<.001.00233
UCECCHEK1 →+0.638+1.699<.001<.00133
UCECFAM177A1 →+0.381+3.491<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,442 associations by consensus.

RNA5SP420 by SNAP91 expression — STAD

Box plot of RNA5SP420 in SNAP91-low vs SNAP91-high samples in STAD.

Explore this box plot interactively →

Exploration