SNAP91

Across TCGA patient cohorts, SNAP91 mutation is significantly associated with the total protein of many other genes, with 55 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNAP91-associated genes across cancer lineages are TFRC, Caspase-7-cleavedD198, and CD49b. Each is linked with SNAP91 in more than 2 cancer types. Because this analysis shows association rather than direction, both SNAP91-to-partner and partner-to-SNAP91 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFRC grouped by SNAP91-low versus SNAP91-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNAP91→partner) and Y-score (partner→SNAP91) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	TFRC →	+0.598	+1.883	.038	.031	3	3
LUSC	Caspase-7-cleavedD198 →	+0.782	+2.594	<.001	.006	3	2
LUSC	CD49b →	+0.381	+3.169	.006	.018	2	3
BRCA	Cyclin-E1 →	+0.492	+2.827	.008	.037	2	3
UCEC	14-3-3_beta →	-0.096	-2.388	.002	.002	3	2
UCEC	eIF4E →	+0.198	+2.115	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 55 associations by consensus.

TFRC by SNAP91 expression — LUSC

Explore this box plot interactively →