SNAP91

Across TCGA cell cohorts, SNAP91 mutation is significantly associated with the RNA expression of many other genes, with 266 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SNAP91-associated genes across cancer lineages are IFNA2, OR8D1, and ODF1. Each is linked with SNAP91 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNAP91-to-partner and partner-to-SNAP91 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IFNA2 grouped by SNAP91-low versus SNAP91-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNAP91→partner) and Y-score (partner→SNAP91) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	IFNA2 →	+0.036	+5.169	<.001	.005	3	2
LUNG_NSCLC_LUAD	OR8D1 →	+0.098	+4.343	<.001	.002	3	2
SKIN	ODF1 →	+0.011	+3.700	<.001	.009	3	2
BREAST	IZUMO3 →	+0.035	+5.169	<.001	.005	3	1
BLOOD_Leukemia	CYP2A13 →	+0.013	+6.569	<.001	<.001	3	1
LUNG_NSCLC_LUAD	NXF5 →	+0.045	+3.847	.005	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 266 associations by consensus.

IFNA2 by SNAP91 expression — BREAST

Explore this box plot interactively →