SNAP47

Across TCGA pan-cancer cohorts, SNAP47 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated SNAP47 data layer compared with 25 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher SNAP47 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated SNAP47 expression acts as an unfavorable survival marker.

LUSC and LUAD are the cancer types where SNAP47 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Median	II,III,IV	0.079	0.750	<.001	18	view →
LUAD	OS	Median	All	0.237	0.787	.014	9	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

SNAP47–LUSC (DFS)

Open the LUSC breakdown →