SNAP47

Across TCGA cell cohorts, SNAP47 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,753 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SNAP47-associated GO terms across cancer lineages are Transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery, U2-type prespliceosome assembly, and Positive regulation of mitotic cytokinesis. Each is linked with SNAP47 in more than 16 cancer types. Because this analysis shows association rather than direction, both SNAP47-to-partner and partner-to-SNAP47 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery grouped by SNAP47-low versus SNAP47-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SNAP47→partner) and Y-score (partner→SNAP47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery →	+0.167	+0.672	.002	.008	3	17
BLOOD_Myeloma	U2-type prespliceosome assembly →	+0.123	+1.087	<.001	.001	3	16
BLOOD_Myeloma	Positive regulation of mitotic cytokinesis →	+0.156	+0.918	<.001	<.001	3	15
STOMACH	Regulation of stem cell population maintenance →	+0.079	+0.643	<.001	<.001	3	15
STOMACH	Epigenetic regulation of gene expression →	+0.082	+0.768	<.001	<.001	3	15
BONE	Transcription initiation-coupled chromatin remodeling →	+0.092	+0.940	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,753 associations by consensus.

Transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery by SNAP47 expression — BONE

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