SNAP47

Across TCGA cell cohorts, SNAP47 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SNAP47-associated genes across cancer lineages are SEL1L2, ATP1B4, and FAM71B. Each is linked with SNAP47 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNAP47-to-partner and partner-to-SNAP47 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SEL1L2 grouped by SNAP47-low versus SNAP47-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNAP47→partner) and Y-score (partner→SNAP47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	SEL1L2 →	+0.013	+4.906	<.001	.006	3	1
OESOPHAGUS	ATP1B4 →	+0.006	+4.906	<.001	.006	3	1
OESOPHAGUS	FAM71B →	+0.006	+4.906	<.001	.006	3	1
OESOPHAGUS	LCE1D →	+0.206	+4.906	<.001	.006	3	1
OESOPHAGUS	KRT28 →	+0.016	+4.906	<.001	.006	3	1
LARGE_INTESTINE	RFX4 →	+0.032	+2.444	.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

SEL1L2 by SNAP47 expression — OESOPHAGUS

Explore this box plot interactively →