SNAP29

Across TCGA patient cohorts, SNAP29 mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNAP29-associated genes across cancer lineages are GATA3, ATM, and Bax. Each is linked with SNAP29 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNAP29-to-partner and partner-to-SNAP29 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GATA3 grouped by SNAP29-low versus SNAP29-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNAP29→partner) and Y-score (partner→SNAP29) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GATA3 →	+0.346	+2.827	<.001	.035	3	1
UCEC	ATM →	-0.856	-3.169	<.001	.020	3	1
UCEC	Bax →	+0.311	+2.817	.018	.036	3	1
UCEC	DJ-1 →	+0.211	+3.169	.020	.020	3	1
UCEC	Rab25 →	-0.550	-3.169	.002	.019	2	1
UCEC	MSH2 →	-0.373	-3.169	.003	.020	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

GATA3 by SNAP29 expression — UCEC

Explore this box plot interactively →