SNAI1

Across TCGA patient cohorts, SNAI1 protein abundance is significantly associated with the RNA expression of many other genes, with 500 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SNAI1-associated genes across cancer lineages are SCRN1, ADAMTS9, and NPAP1P2. Each is linked with SNAI1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNAI1-to-partner and partner-to-SNAI1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SNAI1 versus SCRN1 in PDAC, with a Pearson correlation of -0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNAI1→partner) and Y-score (partner→SNAI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SCRN1 →	-0.976	-0.366	.006	.008	3	1
PDAC	ADAMTS9 →	-0.506	-0.341	.002	.005	3	1
PDAC	NPAP1P2 →	+0.130	+0.619	<.001	.007	3	1
PDAC	TYRO3P →	+0.405	+0.426	.005	.005	3	1
UCEC	CLDN15 →	-0.611	-1.202	.001	<.001	3	1
UCEC	RGS13 →	-1.360	-1.003	.006	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 500 associations by consensus.

SNAI1 vs SCRN1 — PDAC

Explore this scatter interactively →