SNAI1

Across TCGA patient cohorts, SNAI1 mutation is significantly associated with the RNA expression of many other genes, with 178 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SNAI1-associated genes across cancer lineages are RNU105C, RN7SKP33, and LINC01802. Each is linked with SNAI1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SNAI1-to-partner and partner-to-SNAI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU105C grouped by SNAI1-low versus SNAI1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNAI1→partner) and Y-score (partner→SNAI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU105C →	+0.141	+4.969	.006	.004	3	3
SKCM	RN7SKP33 →	+0.058	+4.634	<.001	.003	3	2
SKCM	LINC01802 →	+0.417	+4.199	<.001	<.001	3	2
SKCM	AKR1B10P2 →	+0.038	+5.225	<.001	.001	3	2
UCEC	RNU6-1290P →	+0.284	+4.049	<.001	.008	3	2
UCEC	FKBP14-AS1 →	+0.337	+3.223	.007	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 178 associations by consensus.

RNU105C by SNAI1 expression — CESC

Explore this box plot interactively →