SNAI1

Across TCGA cell cohorts, SNAI1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,492 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SNAI1-associated GO terms across cancer lineages are Transcription by RNA polymerase I, Wound healing, spreading of epidermal cells, and Nuclear transport. Each is linked with SNAI1 in more than 9 cancer types. Because this analysis shows association rather than direction, both SNAI1-to-partner and partner-to-SNAI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription by RNA polymerase I grouped by SNAI1-low versus SNAI1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SNAI1→partner) and Y-score (partner→SNAI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Transcription by RNA polymerase I →	+0.107	+1.140	<.001	<.001	3	10
BLOOD_Leukemia	Wound healing, spreading of epidermal cells →	+0.087	+0.846	.001	<.001	3	10
BLOOD_Lymphoma	Nuclear transport →	+0.058	+0.431	<.001	.005	3	9
BLOOD_Lymphoma	Nucleocytoplasmic transport →	+0.058	+0.431	<.001	.005	3	9
STOMACH	Regulation of protein localization to Cajal body →	+0.066	+0.896	<.001	.006	3	8
STOMACH	Positive regulation of protein localization to Cajal body →	+0.066	+0.896	<.001	.006	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,492 associations by consensus.

Transcription by RNA polymerase I by SNAI1 expression — LARGE_INTESTINE

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