Across TCGA patient cohorts, SMYD4 protein abundance is significantly associated with the RNA expression of many other genes, with 2,345 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SMYD4-associated genes across cancer lineages are RPA1, RAB42, and RPL21P89. Each is linked with SMYD4 in more than 2 cancer types. Because this analysis shows association rather than direction, both SMYD4-to-partner and partner-to-SMYD4 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMYD4→partner) and Y-score (partner→SMYD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RPA1 →	+0.594	+0.273	<.001	<.001	3	3
CCRCC	RAB42 →	+1.395	+0.218	.002	.006	3	2
HNSC	RPL21P89 →	-0.588	-0.445	<.001	<.001	3	2
PDAC	ZNF687-AS1 →	+0.276	+0.502	.006	.004	3	2
LSCC	GSTZ1 →	+0.437	+0.248	.004	<.001	3	2
LSCC	NKAP →	+0.390	+0.250	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,345 associations by consensus.

Exploration

SMYD4 survival (RNA) · tumor vs normal (RNA) · all SMYD4 data types