Across TCGA cell cohorts, SMYD4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,491 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SMYD4-associated GO terms across cancer lineages are Regulation of transcription initiation by RNA polymerase II, Negative regulation of chromosome organization, and mRNA transport. Each is linked with SMYD4 in more than 16 cancer types. Because this analysis shows association rather than direction, both SMYD4-to-partner and partner-to-SMYD4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMYD4→partner) and Y-score (partner→SMYD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of transcription initiation by RNA polymerase II →	+0.085	+0.830	<.001	<.001	3	17
BONE	Negative regulation of chromosome organization →	+0.111	+0.941	<.001	<.001	3	17
OESOPHAGUS	mRNA transport →	+0.121	+0.935	<.001	<.001	3	16
LARGE_INTESTINE	Centrosome separation →	+0.109	+0.882	<.001	<.001	3	16
LUNG_NSCLC_LUSC	Transcription initiation at RNA polymerase II promoter →	+0.073	+0.891	<.001	.002	3	16
BONE	Regulation of DNA biosynthetic process →	+0.104	+1.145	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,491 associations by consensus.

Exploration

SMYD4 survival (RNA) · tumor vs normal (RNA) · all SMYD4 data types