SMYD3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SMYD3 mutation is significantly associated with the RNA expression of many other genes, with 2,503 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SMYD3-associated genes across cancer lineages are RNA5SP23, CFAP97P1, and SNORD70B. Each is linked with SMYD3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SMYD3-to-partner and partner-to-SMYD3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMYD3→partner) and Y-score (partner→SMYD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCRNA5SP23 →+0.300+5.438.001.00233
LIHCCFAP97P1 →+0.125+5.355<.001.00532
LIHCSNORD70B →+0.541+5.186<.001.00732
SKCMGPAA1P1 →+0.026+4.678<.001.00332
READMIR4772 →+0.818+5.421<.001.00532
UCECZNF280B →+0.533+3.332<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,503 associations by consensus.

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