Across TCGA cell cohorts, SMYD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,476 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SMYD3-associated GO terms across cancer lineages are Adaptive immune response, Heme biosynthetic process, and Heme metabolic process. Each is linked with SMYD3 in more than 7 cancer types. Because this analysis shows association rather than direction, both SMYD3-to-partner and partner-to-SMYD3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMYD3→partner) and Y-score (partner→SMYD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Adaptive immune response →	-0.063	-0.679	.003	.005	2	8
BLOOD_Leukemia	Heme biosynthetic process →	+0.075	+1.087	.002	<.001	3	7
LUNG_NSCLC_LUSC	Heme metabolic process →	+0.113	+1.506	.002	.002	2	6
URINARY_TRACT	Tissue homeostasis →	-0.067	-0.977	<.001	<.001	3	5
SKIN	Positive regulation of immune effector process →	-0.056	-0.610	<.001	.001	3	5
SKIN	Immune response-regulating cell surface receptor signaling pathway →	-0.039	-0.642	.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,476 associations by consensus.

Exploration

SMYD3 survival (RNA) · tumor vs normal (RNA) · all SMYD3 data types