SMYD1

Across TCGA patient cohorts, SMYD1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,749 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SMYD1-associated proteins across cancer lineages are RPL18A, RPL3, and RPL32. Each is linked with SMYD1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SMYD1-to-partner and partner-to-SMYD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMYD1 versus RPL18A in GBM, with a Pearson correlation of -0.25.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SMYD1→partner) and Y-score (partner→SMYD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RPL18A →	-0.362	-0.271	<.001	.001	2	4
GBM	RPL3 →	-0.493	-0.318	<.001	<.001	3	3
GBM	RPL32 →	-0.410	-0.204	<.001	.002	3	3
GBM	RPL34 →	-0.651	-0.257	<.001	<.001	3	3
COAD	RPS16 →	-0.323	-0.477	.001	.008	3	3
COAD	ILK →	+0.420	+0.430	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,749 associations by consensus.

SMYD1 vs RPL18A — GBM

Explore this scatter interactively →