SMURF1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SMURF1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,162 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SMURF1-associated proteins across cancer lineages are GTF2I, MEPCE, and TRIP6. Each is linked with SMURF1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SMURF1-to-partner and partner-to-SMURF1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SMURF1→partner) and Y-score (partner→SMURF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMGTF2I →+0.464+0.248<.001<.00136
HNSCMEPCE →+0.336+0.611<.001<.00135
LUADTRIP6 →+0.373+0.630<.001<.00135
BRCATAGLN2 →+0.334+0.375.006.00535
HNSCBAIAP2L1 →+0.585+0.838<.001<.00135
HNSCCUX1 →+0.252+0.672<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,162 associations by consensus.

Exploration