Across TCGA cell cohorts, SMURF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,275 significant associations in total. CNS shows the largest number of these associations.

The most reproducible SMURF1-associated GO terms across cancer lineages are Pre-mRNA catabolic process, Peptidyl-serine phosphorylation, and Regulation of axon extension. Each is linked with SMURF1 in more than 15 cancer types. Because this analysis shows association rather than direction, both SMURF1-to-partner and partner-to-SMURF1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMURF1→partner) and Y-score (partner→SMURF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Pre-mRNA catabolic process →	+0.205	+0.818	.001	<.001	3	16
SOFT_TISSUE	Peptidyl-serine phosphorylation →	+0.077	+1.018	<.001	<.001	3	13
PANCREAS	Regulation of axon extension →	+0.144	+1.297	<.001	.002	3	13
BREAST	Negative regulation of MyD88-dependent toll-like receptor signaling pathway →	+0.623	+0.958	.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.064	+0.763	<.001	.002	3	13
BONE	Negative regulation of toll-like receptor signaling pathway →	+0.097	+0.724	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,275 associations by consensus.

Exploration

SMURF1 survival (RNA) · tumor vs normal (RNA) · all SMURF1 data types