SMU1P1

Across TCGA pan-cancer cohorts, SMU1P1 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of SMU1P1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where SMU1P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SMU1P1 is over-expressed in tumor, although a few such as PAAD and UCEC show the opposite, repressed pattern.

COAD, HNSC, and PAAD are the cancer types where SMU1P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SMU1P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	II,III,IV	+0.305	<.001	7	view →
HNSC	Male	All	+0.067	.016	4	view →
PAAD	Female	All	−0.310	.033	2	view →
UCEC	All	IV	−0.290	.022	2	view →
BRCA	All	III,IV	+0.071	.039	2	view →
THCA	All	All	−0.052	.010	2	view →
BLCA	All	III,IV	+0.090	.033	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

SMU1P1–COAD

Open the COAD breakdown →