SMU1

Across TCGA patient cohorts, SMU1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,308 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SMU1-associated genes across cancer lineages are FANCG, RPS17, and CCNB1IP1. Each is linked with SMU1 in more than 8 cancer types. Because this analysis shows association rather than direction, both SMU1-to-partner and partner-to-SMU1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMU1 versus FANCG in UCEC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMU1→partner) and Y-score (partner→SMU1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FANCG →	+0.475	+0.163	<.001	<.001	3	9
HNSC	RPS17 →	+0.660	+0.170	<.001	.003	3	8
UCEC	CCNB1IP1 →	+0.556	+0.118	<.001	<.001	3	7
LSCC	HELLS →	+0.927	+0.210	<.001	<.001	3	7
HNSC	CCDC77 →	+0.680	+0.179	.003	<.001	3	7
HNSC	RPS10 →	+0.378	+0.143	.003	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,308 associations by consensus.

SMU1 vs FANCG — UCEC

Explore this scatter interactively →