SMU1

Across TCGA cell cohorts, SMU1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,592 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SMU1-associated GO terms across cancer lineages are Import into nucleus, Nuclear transport, and DNA-templated transcription initiation. Each is linked with SMU1 in more than 15 cancer types. Because this analysis shows association rather than direction, both SMU1-to-partner and partner-to-SMU1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Import into nucleus grouped by SMU1-low versus SMU1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMU1→partner) and Y-score (partner→SMU1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Import into nucleus →	+0.081	+0.881	<.001	<.001	3	16
OESOPHAGUS	Nuclear transport →	+0.104	+0.806	.001	<.001	3	15
LUNG_NSCLC_LUSC	DNA-templated transcription initiation →	+0.075	+0.689	<.001	<.001	3	15
OESOPHAGUS	Nucleocytoplasmic transport →	+0.105	+0.806	<.001	<.001	3	15
BLOOD_Lymphoma	Protein import into nucleus →	+0.085	+0.921	<.001	<.001	3	15
BREAST	Positive regulation of cell cycle →	+0.061	+0.632	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,592 associations by consensus.

Import into nucleus by SMU1 expression — BLOOD_Lymphoma

Explore this box plot interactively →