Across TCGA patient cohorts, SMTN protein abundance is significantly associated with the RNA expression of many other genes, with 11,793 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SMTN-associated genes across cancer lineages are MYL9, ACTA2, and CNN1. Each is linked with SMTN in more than 9 cancer types. Because this analysis shows association rather than direction, both SMTN-to-partner and partner-to-SMTN results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMTN→partner) and Y-score (partner→SMTN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MYL9 →	+1.413	+0.774	<.001	<.001	3	10
OV	ACTA2 →	+2.948	+0.998	<.001	<.001	3	10
UCEC	CNN1 →	+2.711	+1.061	<.001	<.001	3	10
UCEC	TAGLN →	+2.076	+0.974	<.001	<.001	3	10
UCEC	ACTG2 →	+2.708	+1.075	<.001	<.001	3	10
HNSC	TPM2 →	+1.755	+0.411	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,793 associations by consensus.

Exploration

SMTN survival (RNA) · tumor vs normal (RNA) · all SMTN data types