Across TCGA cell cohorts, SMTN RNA expression is significantly associated with the RNA expression of many other genes, with 10,548 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SMTN-associated genes across cancer lineages are MICAL3, MYH9, and CSNK1E. Each is linked with SMTN in more than 11 cancer types. Because this analysis shows association rather than direction, both SMTN-to-partner and partner-to-SMTN results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMTN→partner) and Y-score (partner→SMTN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	MICAL3 →	+1.789	+1.904	<.001	<.001	3	12
BONE	MYH9 →	+2.288	+1.606	<.001	<.001	3	12
URINARY_TRACT	CSNK1E →	+1.044	+1.531	.002	.002	2	12
LIVER	NF2 →	+1.397	+1.415	.001	.001	2	12
BONE	YWHAH →	+1.001	+1.973	<.001	<.001	2	12
BONE	DAPK3 →	+1.154	+2.064	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,548 associations by consensus.

Exploration

SMTN survival (RNA) · tumor vs normal (RNA) · all SMTN data types