SMR3B

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SMR3B RNA expression is significantly associated with the go_rna of many other GO terms, with 6,324 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SMR3B-associated GO terms across cancer lineages are Branching morphogenesis of an epithelial tube, Mesenchymal cell proliferation, and Camera-type eye morphogenesis. Each is linked with SMR3B in more than 9 cancer types. Because this analysis shows association rather than direction, both SMR3B-to-partner and partner-to-SMR3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Branching morphogenesis of an epithelial tube grouped by SMR3B-low versus SMR3B-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMR3B→partner) and Y-score (partner→SMR3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADBranching morphogenesis of an epithelial tube →+0.063+0.096<.001<.001310
STADMesenchymal cell proliferation →+0.064+0.108<.001<.001310
STADCamera-type eye morphogenesis →+0.049+0.115<.001<.001210
STADRespiratory system development →+0.064+0.088<.001<.00139
STADNephron development →+0.050+0.131<.001<.001210
STADKidney epithelium development →+0.047+0.126<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,324 associations by consensus.

Branching morphogenesis of an epithelial tube by SMR3B expression — STAD

Box plot of Branching morphogenesis of an epithelial tube in SMR3B-low vs SMR3B-high samples in STAD.

Explore this box plot interactively →

Exploration