SMPX

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SMPX RNA expression is significantly associated with the protein abundance of many other proteins, with 16,793 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SMPX-associated proteins across cancer lineages are BCL3_S41, GPX3, and HMCN1. Each is linked with SMPX in more than 3 cancer types. Because this analysis shows association rather than direction, both SMPX-to-partner and partner-to-SMPX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMPX versus BCL3_S41 in OV, with a Pearson correlation of -0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SMPX→partner) and Y-score (partner→SMPX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVBCL3_S41 →-0.615-0.636.006.00634
PDACGPX3 →+0.696+0.497.001.00234
COADHMCN1 →+0.563+1.035.002.00334
COADKANK2 →+0.502+1.030<.001.00134
PDACKANK2_S375 →+0.484+0.344<.001<.00134
GBMLCMT1 →+0.215+0.316<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,793 associations by consensus.

SMPX vs BCL3_S41 — OV

Per-sample scatter of SMPX vs BCL3_S41 in OV (Pearson r = -0.28).

Explore this scatter interactively →

Exploration