SMPX

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SMPX RNA expression is significantly associated with the go_rna of many other GO terms, with 1,580 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SMPX-associated GO terms across cancer lineages are Mitochondrial inner membrane fusion, Maternal behavior, and Parental behavior. Each is linked with SMPX in more than 4 cancer types. Because this analysis shows association rather than direction, both SMPX-to-partner and partner-to-SMPX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial inner membrane fusion grouped by SMPX-low versus SMPX-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMPX→partner) and Y-score (partner→SMPX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CNSMitochondrial inner membrane fusion →+0.080+0.885<.001<.00135
SOFT_TISSUEMaternal behavior →-0.305-2.510.005<.00135
SOFT_TISSUEParental behavior →-0.305-2.510.005<.00135
KIDNEYSynaptic vesicle endocytosis →+0.075+1.062<.001.00435
BREASTCD8-positive, alpha-beta T cell homeostasis →+0.130+0.737<.001.00735
BREASTPositive regulation of protein maturation →+0.090+0.405.002.00935
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,580 associations by consensus.

Mitochondrial inner membrane fusion by SMPX expression — CNS

Box plot of Mitochondrial inner membrane fusion in SMPX-low vs SMPX-high samples in CNS.

Explore this box plot interactively →

Exploration