SMO

Across TCGA cell cohorts, SMO RNA expression is significantly associated with the RNA expression of many other genes, with 12,054 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SMO-associated genes across cancer lineages are FAM171A2, SEPTIN5, and ARHGEF25. Each is linked with SMO in more than 12 cancer types. Because this analysis shows association rather than direction, both SMO-to-partner and partner-to-SMO results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMO versus FAM171A2 in LIVER, with a Pearson correlation of 0.69.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMO→partner) and Y-score (partner→SMO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	FAM171A2 →	+1.955	+2.614	<.001	<.001	3	13
STOMACH	SEPTIN5 →	+3.431	+3.424	<.001	<.001	3	13
LIVER	ARHGEF25 →	+2.113	+2.073	<.001	.001	3	13
STOMACH	LRP3 →	+3.152	+3.232	<.001	<.001	3	12
BONE	ANKRD6 →	+1.905	+1.762	<.001	<.001	3	12
LUNG_NSCLC_LUSC	TSPAN33 →	+2.765	+3.470	.001	<.001	2	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,054 associations by consensus.

SMO vs FAM171A2 — LIVER

Explore this scatter interactively →