SMLR1

Across TCGA patient cohorts, SMLR1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,924 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SMLR1-associated proteins across cancer lineages are EPB41L2, EPB41L2_S718, and EPB41L2_S550. Each is linked with SMLR1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SMLR1-to-partner and partner-to-SMLR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMLR1 versus EPB41L2 in UCEC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SMLR1→partner) and Y-score (partner→SMLR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EPB41L2 →	+0.451	+0.753	<.001	<.001	3	5
UCEC	EPB41L2_S718 →	+0.783	+0.816	<.001	.001	3	5
LSCC	EPB41L2_S550 →	+0.417	+0.203	<.001	<.001	3	4
GBM	EPB41L2_S715 →	+0.624	+0.648	<.001	<.001	3	4
GBM	GABPA →	+0.178	+0.366	.006	.002	3	4
HNSC	NUB1 →	+0.353	+0.422	<.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,924 associations by consensus.

SMLR1 vs EPB41L2 — UCEC

Explore this scatter interactively →