SMLR1

Across TCGA patient cohorts, SMLR1 protein abundance is significantly associated with the protein abundance of many other proteins, with 1,845 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SMLR1-associated proteins across cancer lineages are RAPH1, RASA3, and RBBP4. Each is linked with SMLR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SMLR1-to-partner and partner-to-SMLR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMLR1 versus RAPH1 in CCRCC, with a Pearson correlation of -0.50.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SMLR1→partner) and Y-score (partner→SMLR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	RAPH1 →	-0.395	-1.266	<.001	<.001	3	1
CCRCC	RASA3 →	-0.197	-0.959	.002	<.001	3	1
CCRCC	RBBP4 →	-0.139	-0.965	<.001	<.001	3	1
CCRCC	RBKS →	+0.407	+0.883	<.001	<.001	3	1
CCRCC	RBM14 →	-0.154	-1.187	<.001	<.001	3	1
CCRCC	RBM15B →	-0.216	-1.094	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,845 associations by consensus.

SMLR1 vs RAPH1 — CCRCC

Explore this scatter interactively →