SMIM6

Across TCGA patient cohorts, SMIM6 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,494 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SMIM6-associated proteins across cancer lineages are LAD1, TJP3, and TKFC. Each is linked with SMIM6 in more than 4 cancer types. Because this analysis shows association rather than direction, both SMIM6-to-partner and partner-to-SMIM6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMIM6 versus LAD1 in CCRCC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM6→partner) and Y-score (partner→SMIM6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	LAD1 →	+0.864	+0.779	.001	<.001	3	5
PDAC	TJP3 →	+0.359	+0.591	<.001	<.001	3	4
PDAC	TKFC →	+0.299	+0.633	<.001	<.001	3	4
LUAD	PBLD →	+0.672	+0.592	<.001	<.001	3	4
HNSC	SH3BGRL2 →	+0.385	+0.789	.001	.004	3	4
UCEC	IFT140 →	+0.422	+1.609	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,494 associations by consensus.

SMIM6 vs LAD1 — CCRCC

Explore this scatter interactively →