Across TCGA patient cohorts, SMIM5 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,343 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SMIM5-associated proteins across cancer lineages are EVPL, MYH14, and SCEL. Each is linked with SMIM5 in more than 5 cancer types. Because this analysis shows association rather than direction, both SMIM5-to-partner and partner-to-SMIM5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM5→partner) and Y-score (partner→SMIM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	EVPL →	+0.734	+0.681	<.001	.001	3	6
HNSC	MYH14 →	+0.745	+0.760	<.001	.001	3	4
OV	SCEL →	+1.036	+0.674	<.001	.002	3	4
LSCC	CGN_S294 →	+1.176	+0.717	<.001	<.001	3	4
HNSC	LLGL2 →	+0.386	+0.606	<.001	.001	3	4
LSCC	EVPL_S2025 →	+0.772	+0.638	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,343 associations by consensus.

Exploration

SMIM5 survival (RNA) · tumor vs normal (RNA) · all SMIM5 data types