Across TCGA patient cohorts, SMIM5 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SMIM5-associated genes across cancer lineages are MIR514B, USP9YP15, and RNA5SP508. Each is linked with SMIM5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SMIM5-to-partner and partner-to-SMIM5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM5→partner) and Y-score (partner→SMIM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR514B →	+0.363	+8.471	<.001	.005	3	1
BRCA	USP9YP15 →	+0.084	+8.471	<.001	.005	3	1
UCEC	RNA5SP508 →	+0.637	+5.694	<.001	.003	3	1
UCEC	RNU7-20P →	+1.484	+5.358	<.001	.006	3	1
UCEC	IGHVIII-2-1 →	+0.151	+6.027	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

SMIM5 survival (RNA) · tumor vs normal (RNA) · all SMIM5 data types